MBS: a genome browser annotation track for high-confident microRNA binding sites in whole human transcriptome.

ABSTRACT: MicroRNAs (miRNAs) are small non-coding ribonucleic acids (RNAs) that play a role in many regulatory pathways in eukaryotes. They usually exert their functions by binding mature messenger RNAs. The prediction of the binding targets of the endogenous miRNAs is crucial to unravel the processes they are involved in. In this work, we performed an extensive miRNA binding sites (MBS) prediction over all the annotated transcript sequences and made them available through an UCSC track. MBS annotation track allows to study and visualize the human miRNA binding sites transcriptome-wide in a genome browser, together with any other available information the user is interested in. In the creation of the database that underlies the MBS track, three consolidated algorithms of miRNA binding prediction hav

SUBMITTER: Arancio W 

PROVIDER: S-EPMC10141451 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature