Linking Copper-Associated Signal Transduction Systems with Their Environment in Marine Bacteria.

ABSTRACT: Copper is an essential trace element for living cells. However, copper can be potentially toxic for bacterial cells when it is present in excess amounts due to its redox potential. Due to its biocidal properties, copper is prevalent in marine systems due to its use in antifouling paints and as an algaecide. Thus, marine bacteria must possess means of sensing and responding to both high copper levels and those in which it is present at only typical trace metal levels. Bacteria harbor diverse regulatory mechanisms that respond to intracellular and extracellular copper and maintain copper homeostasis in cells. This review presents an overview of the copper-associated signal transduction systems in marine bacteria, including the copper efflux systems, detoxification, and chaperone mechanisms.

SUBMITTER: Gautam P 

PROVIDER: S-EPMC10141476 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature