Microwave-Assisted Incorporation of AgNP into Chitosan-Alginate Hydrogels for Antimicrobial Applications.

ABSTRACT: Herein, improving the antibacterial activity of a hydrogel system of sodium alginate (SA) and basic chitosan (CS) using sodium hydrogen carbonate by adding AgNPs was investigated. SA-coated AgNPs produced by ascorbic acid or microwave heating were evaluated for their antimicrobial activity. Unlike ascorbic acid, the microwave-assisted method produced uniform and stable SA-AgNPs with an optimal reaction time of 8 min. Transmission electron microscopy (TEM) confirmed the formation of SA-AgNPs with an average particle size of 9 ± 2 nm. Moreover, UV-vis spectroscopy confirmed the optimal conditions for SA-AgNP synthesis (0.5% SA, 50 mM AgNO₃, and pH 9 at 80 °C). Fourier transform infrared (FTIR) spectroscopy confirmed that the -COO^- group of SA electrostatically interacte

SUBMITTER: Oe T 

PROVIDER: S-EPMC10141964 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature