Taxonomic reclassification of Kaposi Sarcoma identifies disease entities with distinct immunopathogenesis.

ABSTRACT:

Background

The taxonomy of Kaposi Sarcoma (KS) is based on a classification system focused on the description of clinicopathological features of KS in geographically and clinically diverse populations. The classification includes classic, endemic, epidemic/HIV associated and iatrogenic KS, and KS in men who have sex with men (MSM). We assessed the medical relevance of the current classification of KS and sought clinically useful improvements in KS taxonomy.

Methods

We reviewed the demographic and clinicopathological features of 676 patients with KS, who were referred to the national centre for HIV oncology at Chelsea Westminster hospital between 2000 and 2021.

Results

Demographic differences between the different subtypes of KS exist as tautological findings of the cu

SUBMITTER: Openshaw MR 

PROVIDER: S-EPMC10142155 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature