Synthesis of Ni-Doped Tremolite Fibers to Help Clarify the Aetiology of the Cytotoxic Outcome of Asbestos.

ABSTRACT: Asbestos fibers act as complex crystal-chemical reservoirs susceptible of releasing potentially toxic elements (such as ions impurities) into the lung cellular environment during permanency and dissolution. To comprehend the exact pathological mechanisms that are triggered upon inhalation of asbestos fibers, in vitro studies on possible interactions between the mineral and the biological system have been carried out mostly by using natural asbestos. However, this latter comprises intrinsic impurities such as Fe²⁺/Fe³⁺ and Ni²⁺ ions, and other eventual traces of metallic pathogens. Furthermore, often, natural asbestos is characterized by the co-presence of several mineral phases, fiber dimensions of which are randomly distributed in width and in length. For

SUBMITTER: Bloise A 

PROVIDER: S-EPMC10142192 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature