Correlation between Maspin Levels in Different Biological Samples and Pathologic Features in Colorectal Adenocarcinomas.

ABSTRACT: Maspin is an important biomarker which was proven to be correlated to many pathological features that can help the oncologists, the surgeons and also the pathologists for choosing the personalized treatment of the patients. Maspin expression correlates with the budding of colorectal adenocarcinomas that is usually used mostly in immunohistochemistry. In this preliminary study, a small number of patients with clinical and pathological features were selected. Four kinds of samples (tumoral tissues, blood, saliva and urine) were analyzed using a stochastic method using stochastic microsensors. Whole blood maspin concentration values were related to budding, molecular subtype and location. Tissular maspin concentrations were related to location, maxi-mum diameter and pN value from TNM staging

SUBMITTER: Bratei AA 

PROVIDER: S-EPMC10143283 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature