Choline-Containing Phospholipids in Stroke Treatment: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Globally, stroke is the second leading cause of death and disability. In different studies conducted previously, the choline-containing phospholipids citicoline and choline alphoscerate have been proposed as adjuvants in the treatment of acute strokes. A systematic review was conducted to provide updated information on the effects of citicoline and choline alphoscerate in patients with acute and hemorrhagic strokes.

Methods

PubMed/Medline, Scopus, and Web of Science were searched to identify relevant materials. Data were pooled, and odds ratios (OR) were reported for binary outcomes. Using mean differences (MD), we evaluated continuous outcomes.

Results

A total of 1460 studies were reviewed; 15 studies with 8357 subjects met the eligibility criteria and wer

SUBMITTER: Sagaro GG 

PROVIDER: S-EPMC10143951 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature