Associations Between Childhood Obesity and Pubertal Timing Stratified by Sex and Race/Ethnicity.

ABSTRACT: Earlier puberty has been associated with numerous adverse mental, emotional, and physical health outcomes. Obesity is a known risk factor for earlier puberty in girls, but research with boys has yielded inconsistent findings. We examined sex- and race/ethnicity-specific associations between childhood obesity and puberty in a multiethnic cohort of 129,824 adolescents born at a Kaiser Permanente Northern California medical facility between 2003 and 2011. We used Weibull regression models to explore associations between childhood obesity and breast development onset (thelarche) in girls, testicular enlargement onset (gonadarche) in boys, and pubic hair development onset (pubarche) in both sexes, adjusting for important confounders. Clear dose-response relationships were observed. Boys with se

SUBMITTER: Aghaee S 

PROVIDER: S-EPMC10144668 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature