Clinical Evidence for the Use of Octenidine Dihydrochloride to Prevent Healthcare-Associated Infections and Decrease Staphylococcus aureus Carriage or Transmission-A Review.

ABSTRACT:

Background

The antiseptic agent octenidine dihydrochloride (OCT) is used for skin preparation, for Staphylococcus aureus decolonization, and within bundles for the prevention of catheter-related or surgical site infections (SSIs). Here, we review the evidence for the effects of OCT from clinical studies.

Methods

Review of studies published in the Medline, Scopus, and Cochrane databases until August 2022, performed in clinical settings and reporting on effects of OCT on S. aureus carriage/transmission, SSI prevention, and prevention of intensive care unit (ICU)-related or catheter-related bloodstream and insertion site infections.

Results

We included 31 articles. The success of S. aureus decolonization with OCT-containing therapies ranged between 6

SUBMITTER: Kock R 

PROVIDER: S-EPMC10145019 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature