Whole genome analysis of two sympatric human Mansonella: Mansonella perstans and Mansonella sp "DEUX".

ABSTRACT:

Introduction

Mansonella species are filarial parasites that infect humans worldwide. Although these infections are common, knowledge of the pathology and diversity of the causative species is limited. Furthermore, the lack of sequencing data for Mansonella species, shows that their research is neglected. Apart from Mansonella perstans, a potential new species called Mansonella sp "DEUX" has been identified in Gabon, which is prevalent at high frequencies. We aimed to further determine if Mansonella sp "DEUX" is a genotype of M. perstans, or if these are two sympatric species.

Methods

We screened individuals in the area of Fougamou, Gabon for Mansonella mono-infections and generated de novo assemblies from the respective samples. For evoluti

SUBMITTER: Rodi M 

PROVIDER: S-EPMC10145164 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature