DNA-Templated Silver Nanoclusters as Dual-Mode Sensitive Probes for Self-Powered Biosensor Fueled by Glucose.

ABSTRACT: Nanomaterials have been extensively explored in developing sensors due to their unique properties, contributing to the development of reliable sensor designs with improved sensitivity and specificity. Herein, we propose the construction of a fluorescent/electrochemical dual-mode self-powered biosensor for advanced biosensing using DNA-templated silver nanoclusters (AgNCs@DNA). AgNC@DNA, due to its small size, exhibits advantageous characteristics as an optical probe. We investigated the sensing efficacy of AgNCs@DNA as a fluorescent probe for glucose detection. Fluorescence emitted by AgNCs@DNA served as the readout signal as a response to more H₂O₂ being generated by glucose oxidase for increasing glucose levels. The second readout signal of this dual-mode biosensor

SUBMITTER: Gupta AK 

PROVIDER: S-EPMC10145323 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature