Microorganism-Derived Molecules as Enzyme Inhibitors to Target Alzheimer's Diseases Pathways.

ABSTRACT: Alzheimer's disease (AD) is the most common form of dementia. It increases the risk of other serious diseases and causes a huge impact on individuals, families, and socioeconomics. AD is a complex multifactorial disease, and current pharmacological therapies are largely based on the inhibition of enzymes involved in the pathogenesis of AD. Natural enzyme inhibitors are the potential sources for targeting AD treatment and are mainly collected from plants, marine organisms, or microorganisms. In particular, microbial sources have many advantages compared to other sources. While several reviews on AD have been reported, most of these previous reviews focused on presenting and discussing the general theory of AD or overviewing enzyme inhibitors from various sources, such as chemical synthesis,

SUBMITTER: Nguyen TH 

PROVIDER: S-EPMC10146315 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature