Elucidating the Potential Inhibitor against Type 2 Diabetes Mellitus Associated Gene of GLUT4.

ABSTRACT: Diabetes is a chronic hyperglycemic disorder that leads to a group of metabolic diseases. This condition of chronic hyperglycemia is caused by abnormal insulin levels. The impact of hyperglycemia on the human vascular tree is the leading cause of disease and death in type 1 and type 2 diabetes. People with type 2 diabetes mellitus (T2DM) have abnormal secretion as well as the action of insulin. Type 2 (non-insulin-dependent) diabetes is caused by a combination of genetic factors associated with decreased insulin production, insulin resistance, and environmental conditions. These conditions include overeating, lack of exercise, obesity, and aging. Glucose transport limits the rate of dietary glucose used by fat and muscle. The glucose transporter GLUT4 is kept intracellular and sorted dynam

SUBMITTER: Aldahish A 

PROVIDER: S-EPMC10146764 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature