Prevention of the Pro-Aggressive Effects of Ethanol-Intoxicated Mice by Schisandrin B.

ABSTRACT: Excessive alcohol consumption can lead to serious health complications, with liver and neurological complications being the most important. In Western nations, alcoholic liver disease accounts for 50% of mortality from end-stage liver disease and is the second most common cause of liver transplants. In addition to direct damage, hepatic encephalopathy may also arise from alcohol consumption. However, effective treatment for liver disease, as well as neurological injury, is still lacking today; therefore, finding an efficacious alternative is urgently needed. In the current study, the preventive and therapeutic effects of Schisandrin B (Sch B) against ethanol-induced liver and brain injuries were investigated. By using two treatment models, our findings indicated that Sch B can effectively

SUBMITTER: Lam HYP 

PROVIDER: S-EPMC10146817 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature