Yoghurt Intake and Gastric Cancer: A Pooled Analysis of 16 Studies of the StoP Consortium.

ABSTRACT:

Background

Yoghurt can modify gastrointestinal disease risk, possibly acting on gut microbiota. Our study aimed at exploring the under-investigated association between yoghurt and gastric cancer (GC).

Methods

We pooled data from 16 studies from the Stomach Cancer Pooling (StoP) Project. Total yoghurt intake was derived from food frequency questionnaires. We calculated study-specific odds ratios (ORs) of GC and the corresponding 95% confidence intervals (CIs) for increasing categories of yoghurt consumption using univariate and multivariable unconditional logistic regression models. A two-stage analysis, with a meta-analysis of the pooled adjusted data, was conducted.

Results

The analysis included 6278 GC cases and 14,181 controls, including 1179 cardia and 3463 non-ca

SUBMITTER: Collatuzzo G 

PROVIDER: S-EPMC10147010 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature