A prediction model for distant metastasis after isolated locoregional recurrence of breast cancer.

ABSTRACT:

Purpose

The impact of progesterone receptor (PR) status on the prognosis of breast cancer after isolated locoregional recurrence (ILRR) remains unclear. This study evaluated the impact of clinicopathologic factors, including PR status of ILRR, on distant metastasis (DM) after ILRR.

Methods

We retrospectively identified 306 patients with ILRR diagnosed at the National Cancer Center Hospital between 1993 and 2021 from the database. Cox proportional hazards analysis was performed to examine factors associated with DM after ILRR. We developed a risk prediction model based on the number of detected risk factors and estimated survival curves using the Kaplan-Meier method.

Results

During a median follow-up time of 4.7 years after ILRR diagnosis, 86 patients developed DM, and

SUBMITTER: Murata T 

PROVIDER: S-EPMC10147732 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature