Post-diagnostic statin use and breast cancer-specific mortality: a population-based cohort study.

ABSTRACT:

Purpose

Statins are the most widely prescribed cholesterol lowering medications and have been associated with both improved and unchanged breast cancer outcomes in previous studies. This study examines the association between the post-diagnostic use of statins and breast cancer outcomes (death and recurrence) in a large, representative sample of New Zealand (NZ) women with breast cancer.

Methods

Women diagnosed with a first primary breast cancer between 2007 and 2016 were identified from four population-based regional NZ breast cancer registries and linked to national pharmaceutical data, hospital discharges, and death records. Cox proportional hazard models were used to estimate the hazard of breast cancer-specific death (BCD) associated with any post-diagnostic statin use.

SUBMITTER: Scott OW 

PROVIDER: S-EPMC10147735 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature