Expression of SATB1 and SATB2 in the brain of bony fishes: what fish reveal about evolution.

ABSTRACT: Satb1 and Satb2 belong to a family of homeodomain proteins with highly conserved functional and regulatory mechanisms and posttranslational modifications in evolution. However, although their distribution in the mouse brain has been analyzed, few data exist in other non-mammalian vertebrates. In the present study, we have analyzed in detail the sequence of SATB1 and SATB2 proteins and the immunolocalization of both, in combination with additional neuronal markers of highly conserved populations, in the brain of adult specimens of different bony fish models at key evolutionary points of vertebrate diversification, in particular including representative species of sarcopterygian and actinopterygian fishes. We observed a striking absence of both proteins in the pallial region of actinopterygi

SUBMITTER: Lozano D 

PROVIDER: S-EPMC10147777 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature