An observational study on lifestyle and environmental risk factors in patients with acute appendicitis.

ABSTRACT:

Purpose

Acute appendicitis is a common abdominal emergency worldwide. This study aimed at characterizing environmental risk factors influencing the development and severity of acute appendicitis.

Methods

Patients from a Belgian acute appendicitis cohort (n = 374) and healthy controls from the 500 functional genomics (500FG) cohort (n = 513) were compared. Individuals with a history of appendectomy (n = 1067) and without a history of appendectomy (n = 8656) were available from the Nijmegen Biomedical Study (NBS). Questionnaires on demographics, lifestyle and environment were available. Binary logistic regression was used for prediction models.

Results

Fifteen risk factors for developing acute appendicitis were identified. Binary logistic regression showed that 7 were i

SUBMITTER: Peeters T 

PROVIDER: S-EPMC10147974 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature