TMA-Mate: An open-source modular toolkit for constructing tissue microarrays of arbitrary layouts.

ABSTRACT: Biomedical research and quality control procedures often demand a variety of microscopic analysis of numerous formalin-fixed and paraffin-embedded (FFPE) tissue samples from different individuals of both healthy and diseased regions of interest. Depending on the number of samples to be analyzed, conventional processing of each FFPE block separately can be laborious or impracticable. This effort can be drastically reduced by using tissue microarrays (TMAs). TMAs have a wide range of applications and can be considered as a high-throughput method to process up to hundreds of miniaturized tissue samples simultaneously on a single microscopy slide, in order to reduce labor, costs and sample consumption, and to increase results comparability. Several commercial and self-made solutions to fabrica

SUBMITTER: Pazaitis N 

PROVIDER: S-EPMC10148229 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature