Dataset Information

Distribution of uterocervical angles of pregnant women at 16^+ 0 to 23^+ 6 weeks gestation with low risk for preterm birth: first vietnamese cohort of women with singleton pregnancies.

ABSTRACT:

Background

Cervical length (CL) measured by ultrasound in the second trimester is a predictor of spontaneous preterm birth (sPTB). The uterocervical angle (UCA) has recently been suggested as a predictor to identify women at risk of sPTB. The aim of this study was to investigate the UCAs' distribution in singleton pregnant women at 16^+ 0 - 23^+ 6 weeks of gestation with low risk for sPTB.

Methods

This was a prospective cohort study of 1,051 pregnant women with singleton pregnancies at low risk for preterm delivery. Pregnant women with a viable singleton fetus at 16^+ 0 - 23^+ 6 weeks of gestation were enrolled in the study conducted at the Haiphong Hospital of Obstetrics and Gynecology, Vietnam, from 09/2019 to 09/2020. CL and the UCA were assessed using transvaginal ultrasonography (TVS) by a single sonographer. Subjects were followed-up until the end of pregnancy, and maternal and neonatal outcomes were recorded. The UCAs' range and their relationship with gestational age were evaluated using regression analysis. P < 0.05 was considered statistically significant.

Results

The normal range of the UCA (5^th - 95^th percentiles) was 46.47° (95% CI, 40.27°-51.81°) to 127.06° (95% CI, 123.02° - 130.71°). The UCAs in the preterm birth (< 37 weeks) and full-term groups were 117.86° ± 20.25° and 83.80° ± 24.18°, respectively (p < 0.001). Linear regression analysis showed a significant change in the UCA range from 16^+ 0 to 23^+ 6 weeks of gestation (2.51 degrees per week, p < 0.001). The linear function yielded the highest correlation coefficient in the variation rule of the UCA values (r = 0.22). A total of 42/63 (66.7%) patients with preterm birth < 37 weeks had a UCA above the 75^th percentile. The majority of women with preterm birth had a UCA ≥ 95° compared with those with full-term delivery (88.9% vs. 31.3%, p < 0.001).

Conclusions

The results of this study present background information about the normal range of UCA values in singleton pregnant women at 16^+ 0 to 23^+ 6 weeks at low risk for sPTB in this Vietnamese cohort. In this study population at low risk for sPTB, pregnant women with a UCA value ≥ 95^o were also considered at risk for preterm birth.

SUBMITTER: Nguyen THT

PROVIDER: S-EPMC10148387 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature

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Distribution of uterocervical angles of pregnant women at 16<sup>+ 0</sup> to 23<sup>+ 6</sup> weeks gestation with low risk for preterm birth: first vietnamese cohort of women with singleton pregnancies.

Nguyen Thi Hoang Trang THT Vu Van Tam VT Nguyen Vu Quoc Huy VQH

BMC pregnancy and childbirth 20230428 1

<h4>Background</h4>Cervical length (CL) measured by ultrasound in the second trimester is a predictor of spontaneous preterm birth (sPTB). The uterocervical angle (UCA) has recently been suggested as a predictor to identify women at risk of sPTB. The aim of this study was to investigate the UCAs' distribution in singleton pregnant women at 16<sup>+ 0</sup> - 23<sup>+ 6</sup> weeks of gestation with low risk for sPTB.<h4>Methods</h4>This was a prospective cohort study of 1,051 pregnant women with ...[more]

PMID: 37118695

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Project description:BackgroundRespiratory distress is common during transition after birth, but the effect of continuous positive airway pressure applied in the delivery room has not been systematically evaluated in spontaneously breathing term and ≥34+0 weeks' gestation infants.We aimed to compare delivery room continuous positive airway pressure with no delivery room continuous positive airway pressure for term and ≥34+0 weeks' gestation newborn infants at birth.MethodsInformation sources: Medline, Embase, Cochrane Databases, Database of Abstracts of Reviews of Effects, and Cumulative Index to Nursing and Allied Health Literature. The Databases were last searched in October 2021.Eligibility criteria: Randomized, quasi-randomized, interrupted time series, controlled before-after, and cohort studies with English abstracts.Synthesis of results: Two authors independently extracted data, assessed risk of bias, and certainty of evidence. The main outcome was admission to the neonatal intensive care unit (NICU) or higher level of care receiving any positive pressure support. Data were pooled using fixed effects models.Risk of bias: Was assessed using the Cochrane Risk of Bias Tool for randomized trials and the Non-Randomized Studies of Interventions Tool (ROBINS-I) for observational studies.ResultsIn this meta-analysis, two randomized control trials (323 newborns delivered by cesarean section) showed that delivery room continuous positive airway pressure decreased the likelihood of NICU admission (risk ratio (RR) 95% confidence interval (CI) 0.27 (0.11-0.66), p < 0.005) and NICU respiratory support (RR (95% CI) 0.18 (0.05-0.60), p = 0.005) when compared with no delivery room continuous positive airway pressure. However, in two before-after studies (8,476 newborns), delivery room continuous positive airway pressure use was associated with an increased risk of air leak syndrome when compared with no delivery room continuous positive airway pressure.DiscussionCertainty of evidence was very low for all outcomes. Among term and ≥34+0 weeks' gestation infants having or at risk of having respiratory distress, there is insufficient evidence to suggest for or against routine use of continuous positive airway pressure in the delivery room.Funding: No Funding has been received to conduct this study.Clinical Trial Registration: This systematic review has been registered with the International Prospective Register of Systematic Reviews (http://www.crd.york.ac.uk/prospero/) [identifier: CRD42021225812].

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Dataset Information

Distribution of uterocervical angles of pregnant women at 16^+ 0 to 23^+ 6 weeks gestation with low risk for preterm birth: first vietnamese cohort of women with singleton pregnancies.

Background

Methods

Results

Conclusions

Publications

Distribution of uterocervical angles of pregnant women at 16<sup>+ 0</sup> to 23<sup>+ 6</sup> weeks gestation with low risk for preterm birth: first vietnamese cohort of women with singleton pregnancies.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets

Dataset Information

Distribution of uterocervical angles of pregnant women at 16+ 0 to 23+ 6 weeks gestation with low risk for preterm birth: first vietnamese cohort of women with singleton pregnancies.

Background

Methods

Results

Conclusions

Publications

Distribution of uterocervical angles of pregnant women at 16<sup>+ 0</sup> to 23<sup>+ 6</sup> weeks gestation with low risk for preterm birth: first vietnamese cohort of women with singleton pregnancies.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets

Distribution of uterocervical angles of pregnant women at 16^+ 0 to 23^+ 6 weeks gestation with low risk for preterm birth: first vietnamese cohort of women with singleton pregnancies.