Efficacy and safety of carnitine supplementation on NAFLD: a systematic review and meta-analysis.

ABSTRACT:

Background and objective

The efficacy and safety of L-carnitine supplementation on non-alcoholic fatty liver disease (NAFLD) are unclear. This systematic review and meta-analysis aimed to assess the efficacy and safety of L-carnitine supplementation on NAFLD.

Methods

We searched in four databases (PubMed, Embase, Cochrane Library, and Web of Science) from inception to 1 November 2022 (updated on March 20, 2023) for potentially relevant records without language restrictions. We collected information on the first author, publication year, country, setting, study design, population characteristics, duration of follow-up, outcome variables of interest, and sources of funding. We used a modified Cochrane risk of bias tool to assess the risk of bias, used GRADE to assess the certa

SUBMITTER: Liu A 

PROVIDER: S-EPMC10148537 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature