PdPtRu trimetallic nanozymes and application to electrochemical immunosensor for sensitive SARS-COV-2 antigen detection.

ABSTRACT: Herein, a ternary PdPtRu nanodendrite as novel trimetallic nanozyme was reported, which possessed excellent peroxidase-like activity as well as electro-catalytic activity on account of the synergistic effect between the three metals. Based on the excellent electro-catalytic activity of trimetallic PdPtRu nanozyme toward the reduction of H₂O₂, the trimetallic nanozyme was applied to construct a brief electrochemical immunosensor for SARS-COV-2 antigen detection. Concretely, trimetallic PdPtRu nanodendrite was used to modify electrode surface, which not only generated high reduction current of H₂O₂ for signal amplification, but also provided massive active sites for capture antibody (Ab₁) immobilization to construct immunosensor. In the

SUBMITTER: Li Y 

PROVIDER: S-EPMC10148716 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature