Long-term HbA1c variability and macro-/micro-vascular complications in type 2 diabetes mellitus: a meta-analysis update.

ABSTRACT:

Aims

The aim of the present study was to evaluate, by means of a meta-analysis approach, whether new available data, appeared on qualified literature, can support the effectiveness of an association of HbA1c variability with the risk of macro- and/or micro-vascular complications in type 2 diabetes mellitus (T2DM).

Methods

The meta-analysis was conducted according to PRISMA Statement guidelines and considered published studies on T2DM, presenting HbA1c variability as standard deviation (SD) or its derived coefficient of variation (CV). Literature search was performed on PubMed in the time range 2015-July 2022, with no restrictions of language.

Results

Twenty-three selected studies fulfilled the aims of the present investigation. Overall, the analysis of the risk as haz

SUBMITTER: Sartore G 

PROVIDER: S-EPMC10148792 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature