Reproducibility and diurnal variation in middle cerebral artery blood velocity in healthy humans.

ABSTRACT:

New findings

What is the central question of this study? We sought to establish between-day reproducibility in estimates of middle cerebral artery blood velocity (MCAv) and cerebrovascular reactivity (CVR) in young, healthy male and female adults in tightly controlled experimental conditions. What is the main finding and its importance? Measures of MCAv assessed during morning, afternoon and evening hours are reproducible between days. There is diurnal variation in CVR, with values being highest during the evening compared with the morning. Greater diurnal variation in CVR is associated with more efficient sleep and greater nocturnal blood pressure dipping. These data enhance our understanding of modulators of MCAv and CVR.

Abstract

Transcranial Doppler (TCD) is used to asse

SUBMITTER: Shariffi B 

PROVIDER: S-EPMC10148902 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature