Atypical oscillatory dynamics during emotional face processing in paediatric obsessive-compulsive disorder with MEG.

ABSTRACT: Children and youth with obsessive-compulsive disorder (OCD) demonstrate difficulties with social, emotional and cognitive functions in addition to the core diagnosis of obsessions and compulsions. This is the first magnetoencephalography (MEG) study to examine whole-brain neurophysiological functional connectivity of emotional face processing networks in paediatric OCD. Seventy-two participants (OCD: n = 36; age 8-17 yrs; typically developing controls: n = 36, age 8-17 yrs) completed an implicit emotional face processing task in the MEG. Functional connectivity networks in canonical frequency bands were compared between groups, and within OCD and control groups between emotions (angry vs. happy). Between groups, participants with OCD showed increased functional connectivity in the gamma ba

SUBMITTER: Safar K 

PROVIDER: S-EPMC10149418 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature