The effect of environmental factors on precocious puberty in children: a case-control study.

ABSTRACT:

Background

Recently the prevalence of precocious puberty development is increasing among Chinese children. Proper understanding of the risk factors for precocious puberty in children is pivotal as could help to improve children's health. This study aims to evaluate the effect of environmental factors on precocious puberty in children.

Methods

We matched the cases and controls by age at the ratio of 1:1 (201 cases and 201 controls) for girls and 1:4 (24 cases and 96 controls) for boys. We used conditional logistic regression to explore the effect of environmental factors on precocious puberty, and a random forest model to identify the most important risk factor.

Results

In the multivariate regression, cesarean section (OR = 1.99, 95% CI: 1.05, 3.76), child body mass in

SUBMITTER: Bigambo FM 

PROVIDER: S-EPMC10149633 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature