Case report: mRNA-1273 COVID-19 vaccine-associated myopericarditis: Successful treatment and re-exposure with colchicine.

ABSTRACT:

Introduction

Vaccine-induced myocarditis is a rare complication of messenger RNA (mRNA) COVID-19 vaccines.

Case presentation

We report a case of acute myopericarditis in a recipient of allogeneic hematopoietic cells following the first dose of the mRNA-1273 vaccine and the successful administration of a second and third dose while on prophylactic treatment with colchicine to successfully complete the vaccination.

Conclusion

Treatment and prevention of mRNA-vaccine-induced myopericarditis represent a clinical challenge. The use of colchicine is feasible and safe to potentially reduce the risk of this rare but severe complication and allows re-exposure to an mRNA vaccine.

SUBMITTER: Valore L 

PROVIDER: S-EPMC10149711 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature