A proprietary black cumin oil extract (Nigella sativa) (BlaQmax^®) modulates stress-sleep-immunity axis safely: Randomized double-blind placebo-controlled study.

ABSTRACT:

Objective

Stress, sleep, and immunity are important interdependent factors that play critical roles in the maintenance of health. It has been established that stress can affect sleep, and the quality and duration of sleep significantly impact immunity. However, single drugs capable of targeting these factors are limited because of their multi-targeting mechanisms. The present study investigated the influence of a proprietary thymoquinone-rich black cumin oil extract (BCO-5) in modulating stress, sleep, and immunity.

Methods

A randomized double-blinded placebo-controlled study was carried out on healthy volunteers with self-reported non-refreshing sleep issues (n = 72), followed by supplementation with BCO-5/placebo at 200  mg/day for 90  days. Validated questionnaires

SUBMITTER: Mohan ME 

PROVIDER: S-EPMC10149792 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature