Duration of delayed diagnosis in HIV/AIDS patients in Iran: a CD4 depletion model analysis.

ABSTRACT:

Objective

Delayed diagnosis of HIV can lead to an inappropriate response to antiretroviral therapy (ART), rapid progression of the disease, and death. It can also carry harmful effects on public health due to the increment of transmission. This study aimed to estimate the duration of delayed diagnosis (DDD) in HIV patients in Iran.

Methods

This hybrid cross-sectional cohort study was conducted on the national HIV surveillance system database (HSSD). Linear mixed effect models with random intercept, random slope, and both were used to estimate the parameters required for the CD4 depletion model to determine the best-fitted model for DDD, stratified by the route of transmission, gender, and age group.

Results

The DDD was estimated in 11,373 patients including 4,762 (41.

SUBMITTER: Sharafi M 

PROVIDER: S-EPMC10149797 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature