The prevalence and risk factors of anxiety in multiple sclerosis: A systematic review and meta-analysis.

ABSTRACT:

Background

Patients with multiple sclerosis (MS) suffer from repetitive neurological deterioration, while anxiety may play a significant role in the disease's progression.

Objective

To explore the prevalence of anxiety in MS and to investigate the risk factors related to anxiety in MS patients.

Methods

An analysis of four databases, PubMed, Web of Science, EMBASE, and Cochrane Library, has been conducted to determine the prevalence or risk factors for anxiety in MS published before May 2021.

Results

In total, 32 studies were found to be eligible. Anxiety prevalence was estimated to be 36% based on the pooled estimates [the 95% confidence interval (CI) = [0.30-0.42], I ² = 98.4%]. Significant risk factors for developing of anxiety were as follo

SUBMITTER: Zhang X 

PROVIDER: S-EPMC10149809 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature