The epidemiology and evolutionary dynamics of massive dengue outbreak in China, 2019.

ABSTRACT:

Introduction

In 2019, China experienced massive dengue outbreaks with high incidence and expanded outbreak areas. The study aims to depict dengue's epidemiology and evolutionary dynamics in China and explore the possible origin of these outbreaks.

Methods

Records of confirmed dengue cases in 2019 were obtained from the China Notifiable Disease Surveillance System. The sequences of complete envelope gene detected from the outbreak provinces in China in 2019 were retrieved from GenBank. Maximum Likelihood trees were constructed to genotype the viruses. The median-joining network was used to visualize fine-scale genetic relationships. Four methods were used to estimate the selective pressure.

Results

A total of 22,688 dengue cases were reported, 71.4% of which were indig

SUBMITTER: Sang S 

PROVIDER: S-EPMC10149964 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature