The oral microbiome of patients with ischemic stroke predicts their severity and prognosis.

ABSTRACT:

Background and objectives

Stroke is a common group of cerebrovascular diseases that can lead to brain damage or death. Several studies have shown a close link between oral health and stroke. However, the oral microbiome profiling of ischemic stroke (IS) and its potential clinical implication are unclear. This study aimed to describe the oral microbiota composition of IS, the high risk of IS, and healthy individuals and to profile the relationship between microbiota and IS prognosis.

Methods

This observational study recruited three groups: IS, high-risk IS (HRIS), and healthy control (HC) individuals. Clinical data and saliva were collected from participants. The modified Rankin scale score after 90 days was used to assess the prognosis of stroke. Extracted DNA from saliva an

SUBMITTER: Sun W 

PROVIDER: S-EPMC10150016 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature