Tooth loss and the risk of cognitive decline and dementia: A meta-analysis of cohort studies.

ABSTRACT:

Introduction

Epidemiological studies have shown that tooth loss may be associated with an increased risk of cognitive decline and dementia. However, some results do not show a significant association. Therefore, we performed a meta-analysis to evaluate this association.

Methods

Relevant cohort studies were searched in PubMed, Embase, Web of Science (up to May 2022), and the reference lists of retrieved articles. The pooled relative risk (RR) and 95% confidence intervals were computed using a random-effects model (CI). Heterogeneity was evaluated using the I ² statistic. Publication bias was evaluated using the Begg's and Egger's tests.

Results

Eighteen cohort studies met the inclusion criteria. Original studies with 356,297 participants

SUBMITTER: Li L 

PROVIDER: S-EPMC10150074 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature