(A)symmetry during gait initiation in people with Parkinson's disease: A motor and cortical activity exploratory study.

ABSTRACT:

Background

Gait asymmetry and deficits in gait initiation (GI) are among the most disabling symptoms in people with Parkinson's disease (PwPD). Understanding if PwPD with reduced asymmetry during GI have higher asymmetry in cortical activity may provide support for an adaptive mechanism to improve GI, particularly in the presence of an obstacle.

Objective

This study quantified the asymmetry of anticipatory postural adjustments (APAs), stepping parameters and cortical activity during GI, and tested if the presence of an obstacle regulates asymmetry in PwPD.

Methods

Sixteen PwPD and 16 control group (CG) performed 20-trials in two conditions: unobstructed and obstructed GI with right and left limbs. We measured, through symmetry index, (i) motor parameters: APAs and ste

SUBMITTER: Faria MH 

PROVIDER: S-EPMC10150081 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature