Preoperative levels of folate receptor-positive circulating tumor cells in different subtypes of early-stage lung adenocarcinoma: Predictive value for determining extent of surgical resection.

ABSTRACT:

Background

The objective was to measure the correlations of preoperative levels of folate receptor-positive circulating tumor cells (FR⁺CTCs) with clinical characteristics and histologic subtype in early-stage lung adenocarcinoma, and to determine the predictive value of FR⁺CTC level in preoperative determination of the extent of surgical resection.

Patients and methods

In this retrospective, single-institution, observational study, preoperative FR⁺CTC levels were measured via ligand-targeted enzyme-linked polymerization in patients with early-stage lung adenocarcinoma. Receiver operating characteristic (ROC) analysis was used to identify the optimal cutoff value of FR⁺CTC level for prediction of various clinical characteris

SUBMITTER: Zhou C 

PROVIDER: S-EPMC10150082 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature