Efficacy and safety of different JAK inhibitors in the treatment of alopecia areata: a network meta-analysis.

ABSTRACT:

Background

Alopecia areata (AA) is an immune disease characterized by non-scarring hair loss. With the widespread application of JAK inhibitors in immune-related diseases, attention is being given to their role in the treatment of AA. However, it is unclear which JAK inhibitors have a satisfactory or positive effect on AA. This network meta-analysis aimed to compare the efficacy and safety of different JAK inhibitors in the treatment of AA.

Methods

The network meta-analysis was performed according to the PRISMA guidelines. We included randomized controlled trials as well as a small number of cohort studies. The differences in efficacy and safety between the treatment and control groups were compared.

Results

Five randomized controlled trials, two retrospective studies

SUBMITTER: Wei D 

PROVIDER: S-EPMC10150113 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature