SNV-FEAST: microbial source tracking with single nucleotide variants.
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ABSTRACT:
SUBMITTER: Briscoe L
PROVIDER: S-EPMC10150486 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
Publications
SNV-FEAST: microbial source tracking with single nucleotide variants.
Briscoe Leah L Halperin Eran E Garud Nandita R NR
Genome biology 20230430 1
Elucidating the sources of a microbiome can provide insight into the ecological dynamics responsible for the formation of these communities. Source tracking approaches to date leverage species abundance information; however, single nucleotide variants (SNVs) may be more informative because of their high specificity to certain sources. To overcome the computational burden of utilizing all SNVs for a given sample, we introduce a novel method to identify signature SNVs for source tracking. Signatur ...[more]
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