Identification of atypical sleep microarchitecture biomarkers in children with autism spectrum disorder.

ABSTRACT:

Importance

Sleep disorders are one of the most frequent comorbidities in children with autism spectrum disorder (ASD). However, the link between neurodevelopmental effects in ASD children with their underlying sleep microarchitecture is not well understood. An improved understanding of etiology of sleep difficulties and identification of sleep-associated biomarkers for children with ASD can improve the accuracy of clinical diagnosis.

Objectives

To investigate whether machine learning models can identify biomarkers for children with ASD based on sleep EEG recordings.

Design setting and participants

Sleep polysomnogram data were obtained from the Nationwide Children' Health (NCH) Sleep DataBank. Children (ages: 8-16 yrs) with 149 autism and 197 age-matched controls with

SUBMITTER: Martinez C 

PROVIDER: S-EPMC10150704 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature