Different effects of vaccine on VST in critical and non-critical COVID-19 patients: A retrospective study of 363 cases.

ABSTRACT:

Aim

To explore the risk factors of prolonged viral shedding time (VST) in critical/non-critical COVID-19 patients during hospitalization.

Methods

In this retrospective study, we enrolled 363 patients with SARS-CoV-2 infection admitted in a designated hospital during the COVID-19 outbreak in Nanjing Lukou International Airport. Patients were divided into critical (n = 54) and non-critical (n = 309) groups. We analyzed the relationship between the VST and demographics, clinical characteristics, medications, and vaccination histories, respectively.

Results

The median duration of VST was 24 d (IQR, 20-29) of all patients. The VST of critical cases was longer than non-critical cases (27 d, IQR, 22.0-30.0 vs. 23 d, IQR 20-28, P < 0.05). Cox proportional hazards model showed

SUBMITTER: Ying-Hao P 

PROVIDER: S-EPMC10151027 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature