The Role of Benralizumab in Eosinophilic Immune Dysfunctions: A Case Report-Based Literature Review.

ABSTRACT: In the past years, the knowledge of eosinophils playing a primary pathophysiologic role in several associated conditions has led to the development of biologics targeting therapies aiming at normalizing the immune response, reducing chronic inflammation, and preventing tissue damage. To better illustrate the potential relationship between different eosinophilic immune dysfunctions and the effects of biological therapies in this scenario, here, we present a case of a 63-year-old male first referred to our department in 2018 with a diagnosis of asthma, polyposis, and rhinosinusitis and presenting a suspicion of nonsteroidal anti-inflammatory drugs' allergy. He also had a past medical history of eosinophilic gastroenteritis/duodenitis (eosinophilia counts >50 cells/high-power field HPF). The

SUBMITTER: Gomes M 

PROVIDER: S-EPMC10151146 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature