A single dose of hydrocortisone does not alter interhemispheric transfer of information or transcallosal integration.

ABSTRACT: Stress has been suggested as a factor that may explain the link between altered functional lateralization and psychopathology. Modulation of the function of the corpus callosum via stress hormones may be crucial in this regard. Interestingly, there is evidence that interhemispheric integration and hemispheric asymmetries are modifiable by endocrinological influences. In previous studies, our group could show an enhancing effect of acute stress on interhemispheric integration. To investigate if this effect can be attributed to an increase in the stress hormone cortisol, 50 male participants received 20 mg hydrocortisone or a placebo in a double-blind crossover design. In each test session, we collected EEG data while participants completed a lexical decision task and a Poffenberger paradigm

SUBMITTER: Berretz G 

PROVIDER: S-EPMC10151494 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature