Ghrelin Modifies the Impact of Life Stress on Suicidality in Patients With Acute Coronary Syndrome.

ABSTRACT:

Objective

This study investigated associations of life stressors and serum ghrelin levels with suicidal ideation (SI), and evaluated the potential mediating effect of ghrelin on associations between life stressors and SI in patients with acute coronary syndrome (ACS).

Methods

In total, 969 ACS patients recruited from a tertiary university hospital in Korea within 2 weeks of disease onset were evaluated in terms of life stressors (using the List of Threatening Events Questionnaire), serum ghrelin levels, and SI (using the "suicidal thoughts" item of the Montgomery-Asberg Depression Rating Scale). Covariates included sociodemographics, depression, vascular risk factors, and disease severity. After 1 year, 711 patients were re-evaluated in terms of SI; logistic regression was p

SUBMITTER: Kim JM 

PROVIDER: S-EPMC10151666 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature