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The role of booster vaccination in decreasing COVID-19 age-adjusted case fatality rate: Evidence from 32 countries.


ABSTRACT:

Background

The global COVID-19 pandemic is still ongoing, and cross-country and cross-period variation in COVID-19 age-adjusted case fatality rates (CFRs) has not been clarified. Here, we aimed to identify the country-specific effects of booster vaccination and other features that may affect heterogeneity in age-adjusted CFRs with a worldwide scope, and to predict the benefit of increasing booster vaccination rate on future CFR.

Method

Cross-temporal and cross-country variations in CFR were identified in 32 countries using the latest available database, with multi-feature (vaccination coverage, demographic characteristics, disease burden, behavioral risks, environmental risks, health services and trust) using Extreme Gradient Boosting (XGBoost) algorithm and SHapley Additive

SUBMITTER: Zhou C 

PROVIDER: S-EPMC10151823 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature