Oral anticoagulant switching in patients with atrial fibrillation: a scoping review.

ABSTRACT:

Introduction

Oral anticoagulants (OACs) prevent stroke in patients with atrial fibrillation (AF). Several factors may cause OAC switching.

Objectives

To examine the phenomenon of OAC switching in patients with AF, including all available evidence; frequency and patterns of switch, clinical outcomes, adherence, patient-reported outcomes, reasons for switch, factors associated with switch and evidence gaps.

Design

Scoping review.

Data sources

MEDLINE, Embase and Web of Science, up to January 2022.

Results

Of the 116 included studies, 2/3 examined vitamin K antagonist (VKA) to direct-acting OAC (DOAC) switching. Overall, OAC switching was common and the definition of an OAC switch varied across. Switching from VKA to dabigatran was the most prevalent switch

SUBMITTER: Adelakun AR 

PROVIDER: S-EPMC10151984 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature