Complementary contribution of the medial and lateral human parietal cortex to grasping: a repetitive TMS study.

ABSTRACT: The dexterous control of our grasping actions relies on the cooperative activation of many brain areas. In the parietal lobe, 2 grasp-related areas collaborate to orchestrate an accurate grasping action: dorsolateral area AIP and dorsomedial area V6A. Single-cell recordings in monkeys and fMRI studies in humans have suggested that both these areas specify grip aperture and wrist orientation, but encode these grasping parameters differently, depending on the context. To elucidate the causal role of phAIP and hV6A, we stimulated these areas, while participants were performing grasping actions (unperturbed grasping). rTMS over phAIP impaired the wrist orientation process, whereas stimulation over hV6A impaired grip aperture encoding. In a small percentage of trials, an unexpected reprogrammin

SUBMITTER: Breveglieri R 

PROVIDER: S-EPMC10152058 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature