Spectral specificity of gamma-frequency transcranial alternating current stimulation over motor cortex during sequential movements.

ABSTRACT: Motor control requires the coordination of spatiotemporally precise neural oscillations in the beta and gamma range within the primary motor cortex (M1). Recent studies have shown that motor performance can be differentially modulated based on the spectral target of noninvasive transcranial alternating current stimulation (tACS), with gamma-frequency tACS improving motor performance. However, the spectral specificity for eliciting such improvements remains unknown. Herein, we derived the peak movement-related gamma frequency in 25 healthy adults using magnetoencephalography and a motor control paradigm. These individualized peak gamma frequencies were then used for personalized sessions of tACS. All participants completed 4 sessions of high-definition (HD)-tACS (sham, low-, peak-, and high

SUBMITTER: Spooner RK 

PROVIDER: S-EPMC10152093 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature