Association between prenatal alcohol exposure and children's facial shape: a prospective population-based cohort study.

ABSTRACT:

Study question

Is there an association between low-to-moderate levels of prenatal alcohol exposure (PAE) and children's facial shape?

Summary answer

PAE before and during pregnancy, even at low level (<12 g of alcohol per week), was found associated with the facial shape of children, and these associations were found attenuated as children grow older.

What is known already

High levels of PAE during pregnancy can have significant adverse associations with a child's health development resulting in recognizably abnormal facial development.

Study design, size, duration

This study was based on the Generation R Study, a prospective cohort from fetal life onwards with maternal and offspring data. We analyzed children 3-dimensional (3D) facial images taken at ages 9 (n

SUBMITTER: Liu X 

PROVIDER: S-EPMC10152169 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature