Offspring physiology following the use of IVM, IVF and ICSI: a systematic review and meta-analysis of animal studies.

ABSTRACT:

Background

Since the birth of the first baby using IVF technology in 1978, over 10 million children have been conceived via ART. Although most aspects of ARTs were developed in animal models, the introduction of these technologies into clinical practice was performed without comprehensive assessment of their long-term safety. The monitoring of these technologies over time has revealed differences in the physiology of babies produced using ARTs, yet due to the pathology of those presenting for treatment, it is challenging to separate the cause of infertility from the effect of treatments offered. The use of systematic review and meta-analysis to investigate the impacts of the predominant ART interventions used clinically in human populations on animals produced in healthy fertile po

SUBMITTER: Beilby KH 

PROVIDER: S-EPMC10152177 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature