Decreased breathing variability is associated with poorer outcome in mechanically ventilated patients.

ABSTRACT:

Rationale

Breathing is a cyclic activity that is variable by nature. Breathing variability is modified in mechanically ventilated patients. We aimed to evaluate whether decreased variability on the day of transition from assist-control ventilation to a partial mode of assistance was associated with a poorer outcome.

Methods

This was an ancillary study of a multicentre, randomised, controlled trial comparing neurally adjusted ventilatory assist to pressure support ventilation. Flow and the electrical activity of the diaphragm (EAdi) were recorded within 48 h of switching from controlled ventilation to a partial mode of ventilatory assistance. Variability of flow and EAdi-related variables were quantified by the coefficient of variation, the amplitude ratio of the spectrum's f

SUBMITTER: Rolland-Debord C 

PROVIDER: S-EPMC10152249 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature